Part 1 Egg Donation 101 & What to Look for in an Egg Donor A Quick Overview By Guest Blogger Eran Amir

Egg donation can provide the missing link for those struggling to conceive, who want to avoid passing down a genetic disease, or for singles and gay couples who know they cannot conceive on their own. In this article, we’ll explain in more detail what the egg donation process looks like, how egg donors are screened, the factors to consider in your search for the ideal egg donor and the differences between fresh and frozen donor eggs.

The egg donation process - a quick overview

Through egg donation, a donor chosen by the intended parents provides her eggs to be transferred via IVF. Fertility clinics follow a rigorous screening process when it comes to clearing egg donors. Prior to starting the egg donation process, the egg donor undergoes a thorough medical screening to ensure that she is fit to receive the stimulation medication required (more on this below). Her egg reserve is assessed, and her medical history and family and genetic history evaluated. Blood tests are done to check for undiagnosed medical conditions or infectious diseases.

Once the egg donor is cleared by the clinic, she is prescribed hormone medications to stimulate ovulation and the production of multiple eggs. If it’s a fresh cycle, the intended mother will be prescribed estrogen and progesterone to build up the uterine lining and prepare it for implantation.

The next step is the egg retrieval and fertilization with sperm from the intended father or a sperm donor. The best embryo is transferred to the uterus using a thin catheter, a procedure known as a fresh embryo transfer (FET). The intended mother continues her medication (progesterone). If the transfer is successful, once a heartbeat is confirmed, the pregnancy progresses from there, hopefully making it successfully to term.

While there are various reasons why the use of an egg donor may be recommended, the first step is to understand if egg donation is right for you. 

Is egg donation right for you?

Deciding to grow your family via egg donation is not easy, however it may be an ideal solution if conceiving naturally isn’t possible. The first step is to consult a reproductive endocrinologist (RE) or your fertility clinic to go over your options. Egg donation may be recommended in the following scenarios:

1. Advanced age: fertility naturally diminishes with age as changes start occurring in the ovaries
2. Diminished Ovarian Reserve (DOR): when the ovaries no longer produce quality eggs in adequate numbers. This generally occurs with ageing and menopause, but genetic abnormalities, medical treatments or injury may also lead to an earlier DOR 
3. Primary Ovarian Insufficiency (POI): women naturally experience reduced fertility around 40 years old but for those with POI, this starts earlier - in some cases even as early as the teenage years
4. Absence of the ovaries: due to surgery or a congenital malformation
5. Poor oocyte quality: an oocyte is an immature egg cell. During ovulation, the oocyte matures and becomes an egg. The number of oocytes decreases with age, as does their quality 
6. Poor embryo quality: this could be due to a genetic abnormality in the egg or sperm of the male or female partner, or a genetic abnormality in the embryo
7. Prevention of genetic diseases: if the intended parent is aware of a condition that could be inherited by the baby
8. Previous IVF failure: when IVF was attempted using one’s own eggs
9. Men: who are single or in a same sex relationship need the help of donor eggs to conceive

If a medical issue is keeping you from growing your family, the news that you will need an egg donor can be difficult to take. It’s important that, if necessary, you seek support to come to terms with the news and to discuss the way forward. It’s also completely understandable that you may feel wary of using an egg donor for some time, but chances are the desire to have a baby will help you overcome your reservations and concerns. 

So, give yourself the time you need. Remember that, donor eggs or not, you will still 1,000,000% be your child’s parent. And then once you and your partner feel ready, it’s time to start searching for the ideal egg donor, one that matches all of your preferences.

Look for Part 2 Factors to consider when selecting an egg donor

About Eran Amir

With more than 20 years of experience, Eran Amir has worked as both a software development and product management executive in Israel and the Greater New York Area. The development of GoStork combines his professional skill set with a personal mission. After undergoing a long, difficult, and costly process to expand his family via surrogacy and egg donation, Amir vowed to help other intended parents avoid the complexity and confusion he experienced. His passion led to the creation of GoStork, which proudly names Amir’s two-year-old daughter as its co-founder.