Choosing Between Frozen or Fresh Donor Eggs
Both fresh donor eggs and frozen donor eggs have specific pros and cons which you should consider:
Advantages of using fresh donor eggs
- Better odds of live birth – IVF with fresh donor eggs has been widely researched and found effective. A national study published in the journal Obstetrics and Gynecology found that the use of fresh donor eggs in IVF has a small advantage in birth outcomes. According to the study’s lead author, Jennifer L. Eaton, M.D., “the odds of a good birth outcome were less with frozen than with fresh, but it was a small difference.” Data from the Centers for Disease Control and Prevention (CDC) also shows that, overall, 55.3% of embryo transfers from fresh donor eggs resulted in a live birth vs. 46.7% for embryo transfers from frozen donor eggs.
- Larger number of eggs – A fresh egg donation cycle will give intended parents anywhere from ten to twenty eggs. This is ideal if you plan on having more than one child: a fresh donation cycle will likely provide you with a good number of embryos to pursue more than one pregnancy.
- No need for ICSI - with frozen eggs, an extra procedure known as intracytoplasmic sperm injection (ICSI) becomes a must (which also adds to the overall cost). The freezing and thawing process makes the shell surrounding the egg hard for the sperm to penetrate on its own. ICSI bypasses this as a single sperm is injected directly into the egg.
Caveats with fresh donor eggs
- Longer timeline – using fresh donor eggs is a longer process: it takes time to match a donor to the recipient and then to synchronize schedules and cycles.
- Greater cost – fresh donor egg IVF is typically more expensive than the frozen alternative: as noted by what to expect, at an average of $25,000, fresh donor eggs amount to around twice the cost of frozen eggs.
- Potential for cancellation – donation cycles can on occasion get cancelled due to poor medication response or issues, or because of an insufficient amount of eggs obtained. Medical issues more specifically may include uterine cysts or bleeding, which can have a negative impact on implantation, preventing the cycle’s success.
Ultimately, when it comes to choosing between fresh or frozen eggs, it all comes down to your personal situation. There is no easy answer as to which is best. Success rates can depend on each individual’s specific case, as well as the expertise of the clinic you’re working with. A doctor and the clinic can help you assess your options based on your medical history and specific circumstances.
We hope that this helped provide the information you need. And remember - the right decision is whatever feels right for you. All the best on your journey!
Be sure to also read parts 1 and 2 of Egg Donation 101
About Eran Amir
With more than 20 years of experience, Eran Amir has worked as both a software development and product management executive in Israel and the Greater New York Area. The development of GoStork combines his professional skill set with a personal mission. After undergoing a long, difficult, and costly process to expand his family via surrogacy and egg donation, Amir vowed to help other intended parents avoid the complexity and confusion he experienced. His passion led to the creation of GoStork, which proudly names Amir’s two-year-old daughter as its co-founder.
